Kyle defeated the Horseman War, but was only seconds too late to save Sims from decapitation by Famine. Bella sent out his two of his four horsemen to take care of them. Only Sims and Kyle were left when they were able to enter the church.

Unfortunately Sims lost all his men after Father Bella, the mastermind behind the drug, threw grenades at them while simultaneously a small army of Glowheads attacked them. When Sims traced the source of GLOW to a church in Little Italy during the city riots, Sims along with Kyle and whatever officers he had left attempted to storm the church. Sims also sought to arrest Cody for using GLOW, a highly addictive drug that increases the physical attributes of the user. He wanted Kyle not to get involved due to the danger Cody was in. By the request of his sister, Vanessa, he assisted her boyfriend, Kyle into looking for his missing brother. Sergeant Sims - He is a deep cover cop for the MCPD (Metro City Police Department).While Vanessa tends to Kyle and Cody in the hospital, she keeps her brother’s badge as a remembrance. Kyle eventually saved Cody and the city, but the end result cost her the bar and the life of her brother Sergeant Sims in the final battles. During the GLOW-induced riots in Metro City, Kyle and ex- Mad Gear member 2-Ill (formerly known as Two P) saved her life. She also has her brother on the MCPD in aiding Kyle in his search. When Kyle’s brother, Cody, is taken captive by The Stiff in her bar, Vanessa does her best to provide information and ideas to Kyle to find Cody. Vanessa Sims - is the girlfriend of Kyle and the owner and bartender of the Barfly Lounge in Metro City.

Progress will resume at the last checkpoint rather than the character's last position. The game's save system can only be used once the player decides to quit the game. However, the game is over when the life bar is empty. Kyle, Cody, Guy and Haggar are all playable characters in arcade mode.

It does not have upgradable movesets, counters or instinct abilities. The arcade mode is a no-frills 3D brawler for 1 or 2 players. An 'instinct' system allows players to counter opponents' attacks, as well as make their attacks more powerful. Players earn money through pit fights and side missions, upgrading Kyle's moveset by training in various gyms in Metro City while progressing through the game. The story mode, which is exclusively single player, has ten minigames, including cockroach stomping, arm-wrestling, slide puzzles, shooting contests and the classic car bash. Shocking story twists and disturbing connections are made as this epic story unfolds through adrenaline-pumping action and intense cinematics.Final Fight: Streetwise is a 3D beat 'em up game. Explore dynamic environments and encounter intense street fights where players use hand-to-hand and weapon combat. Featuring stylized and realistic visuals, the tumultuous energy of Metro City is brought to life with great detail. A major element to the game is quickly building 'respect.' Earning this sought-after characteristic gives gamers a means to attain powerful new fighting skills, hardcore weapons, critical information and a wide variety of NPC (non-playable character) support vital for completing various objectives. As a streetwise underground pit fighter and brother of the infamous Cody from the classic Final Fight series, Kyle must try to solve his brother's disappearance. A major element to the game is quickly building 'respect.' In Final Fight: Streetwise, players assume the role of Kyle Travers. Summary: In Final Fight: Streetwise, players assume the role of Kyle Travers.

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